Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TPH1 | P17752 | 2/20 | 0.40 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982506 | 0.87 | MEN1 (0.43) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL7743868 | 0.71 | PDE4A (0.46) | ALDH1A1PKMHTTPDE4APDE4B | |
| SCHEMBL7743866 | 0.71 | PDE4A (0.46) | ALDH1A1PKMHTTPDE4APDE4B | |
| SCHEMBL7744419 | 0.69 | PDE4A (0.47) | KMT2AALDH1A1PKMPDE4APDE4B | |
| SCHEMBL7744421 | 0.69 | PDE4A (0.47) | KMT2AALDH1A1PKMPDE4APDE4B | |
| SCHEMBL21389577 | 0.68 | MEN1 (1.00) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL18159000 | 0.64 | HPGD (0.49) | HPGD | |
| SCHEMBL15810628 | 0.64 | HPGD (0.49) | HPGD | |
| SCHEMBL15798913 | 0.64 | HPGD (0.49) | HPGD | |
| SCHEMBL18852587 | 0.64 | HPGD (0.49) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708781-B1 | A 3 ADENOSINE RECEPTOR AGONISTS | USA (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-0708781-A1 | A 3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 1996-05-01 | — | — | EP | disclosed |