Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316164 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL3851805 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL317668 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL17817820 | 1.00 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL7078310 | 0.95 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL587098 | 0.95 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL160866 | 0.95 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL17967705 | 0.95 | TSHR (0.50) | TSHRALDH1A1LMNAPLA2G2ATP53 | |
| SCHEMBL17627330 | 0.92 | ESR1 (0.56) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL615768 | 0.92 | ESR1 (0.56) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2041-H1 | OVERCOATING WITH LATEX | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-08-06 | — | — | US | disclosed |