SCHEMBL774461

SCHEMBL774461

CO[Si](C)(C)O[SiH2]CCCNCCN

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.39
CA6 P23280 5/20 0.39
CA7 P43166 5/20 0.39
CA9 Q16790 5/20 0.39
CA14 Q9ULX7 5/20 0.39
CA5B Q9Y2D0 5/20 0.39
CA2 P00918 4/20 0.39
CA4 P22748 4/20 0.39
CA5A P35218 4/20 0.39
CA3 P07451 3/20 0.39
MEN1 O00255 2/20 0.37
RECQL P46063 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
ALOX15 P16050 3/20 0.36
CA1 P00915 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331901 0.83 CA12 (0.41) CA12CA6CA7CA9CA14
SCHEMBL3184577 0.82 CA12 (0.44) CA12CA6CA7CA9CA14
SCHEMBL19669 0.78 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL30065157 0.76 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL27591294 0.76 CA12 (0.46) CA12CA6CA7CA9CA14
SCHEMBL8206827 0.76 CA12 (0.48) CA12CA6CA7CA9CA14
SCHEMBL464868 0.75 CA12 (0.37) CA12CA6CA7CA9CA14
SCHEMBL17491638 0.75 CA12 (0.43) CA12CA6CA7CA9CA14
SCHEMBL464862 0.74 CA12 (0.39) CA12CA6CA7CA9CA14
SCHEMBL31297376 0.73 CA12 (0.52) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034946-B2 Direct-to-metal and exterior durable non-skid coating THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-05-19 US claimed
US-9006307-B2 Direct to-metal and exterior durable non-skid coating THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-04-14 US claimed
EP-3286277-B1 EXTERIOR DURABLE SILOXANE-BASED NONSKID/NONSLIP COATING US GOV SEC NAVY (US) 2021-05-26 EP disclosed
EP-3286277-A1 EXTERIOR DURABLE SILOXANE-BASED NONSKID/NONSLIP COATING The Government of the United States of America, as represented by the Secretary of the Navy (US) 2018-02-28 EP disclosed
WO-2016171781-A1 EXTERIOR DURABLE SILOXANE-BASED NONSKID/NONSLIP COATING THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-10-27 WO disclosed
US-9034946-B2 Direct-to-metal and exterior durable non-skid coating THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-05-19 US disclosed
US-9006307-B2 Direct to-metal and exterior durable non-skid coating THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2015-04-14 US disclosed
US-20120238666-A1 Direct-To-Metal and Exterior Durable Non-Skid Coating THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY 2012-09-20 US disclosed
WO-2012039706-A2 A DIRECT-TO-METAL AND EXTERIOR DURABLE NON-SKID COATING SCIENCE APPLICATIONS INTERNATIONAL CORPORATION (US) 2012-03-29 WO disclosed
US-20120071582-A1 DIRECT-TO-METAL AND EXTERIOR DURABLE NON-SKID COATING SCIENCE APPLICATIONS INTERNATIONAL CORPORATION 2012-03-22 US disclosed