⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950469 | 0.77 | — | — | |
| SCHEMBL28977446 | 0.73 | — | — | |
| SCHEMBL7369099 | 0.68 | — | — | |
| SCHEMBL27859733 | 0.64 | — | — | |
| SCHEMBL14357978 | 0.62 | — | — | |
| SCHEMBL28291544 | 0.60 | — | — | |
| SCHEMBL1541107 | 0.59 | — | — | |
| SCHEMBL31496752 | 0.58 | — | — | |
| SCHEMBL31194779 | 0.58 | — | — | |
| SCHEMBL27893545 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097147-A4 | NOVEL ANGIOGENESIS INHIBITORS | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-1097147-A1 | NOVEL ANGIOGENESIS INHIBITORS | Merck & Co., Inc. (US) | 2001-05-09 | — | — | EP | disclosed |
| US-6228871-B1 | THIAZOLE OR OXAZOLE DERIVATIVE TYROSINE KINASE INHIBITORS; ANTICARCINOGENIC AGENTS; AUTOIMMUNE DISEASES; DIABETIC RETINOPATHY | MERCK & CO., INC. | 2001-05-08 | — | — | US | disclosed |
| WO-2000002871-A1 | NOVEL ANGIOGENESIS INHIBITORS | MERCK & CO., INC. (US) | 2000-01-20 | — | — | WO | disclosed |
| US-5166349-A | CHIRAL ORGANOIRON COMPLEXES AND USE FOR ASSYMETRIC REDUCTION | THE BRITISH PETROLEUM COMPANY, P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| WO-1991006550-A1 | CHIRAL ORGANOMETALLIC COMPLEXES AND USES THEREOF | THE BRITISH PETROLEUM COMPANY PLC (GB) | 1991-05-16 | — | — | WO | disclosed |
| EP-0426474-A1 | Chiral organometallic complexes and uses thereof | The British Petroleum Company p.l.c. (GB) | 1991-05-08 | — | — | EP | disclosed |