Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087464 | 0.83 | NR4A2 (0.56) | PKMALOX15CASP1HSD17B10NR4A2 | |
| SCHEMBL10608500 | 0.78 | KMT2A (0.49) | PKMKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL1457404 | 0.78 | KMT2A (0.49) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL15209940 | 0.76 | MALT1 (0.47) | KMT2AKDM4EMEN1OPRK1 | |
| SCHEMBL8052663 | 0.76 | KMT2A (0.47) | PKMKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8043513 | 0.76 | KMT2A (0.52) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL10967579 | 0.76 | KMT2A (0.52) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL1491099 | 0.75 | NR4A2 (0.55) | PKMALOX15CASP1HSD17B10NR4A2 | |
| SCHEMBL19642995 | 0.74 | NR4A2 (0.56) | PKMALOX15CASP1HSD17B10NR4A2 | |
| SCHEMBL8040568 | 0.72 | KMT2A (0.47) | HSD17B10KMT2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002385-A1 | 1-(QUINOLIN-4-YL)-1H-PYRAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-01-11 | — | — | WO | claimed |