Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132512 | 0.92 | TSHR (0.37) | ALDH1A1TSHRDPP4EPHX1 | |
| SCHEMBL11096081 | 0.81 | MAPT (0.31) | DPP4 | |
| SCHEMBL15229117 | 0.81 | MAPT (0.34) | PDE4ATSHRCYP1A2 | |
| SCHEMBL15229605 | 0.79 | CYP1A2 (0.33) | PDE4ATSHRCYP1A2 | |
| SCHEMBL15229723 | 0.78 | CYP1A2 (0.35) | PDE4ATSHRCYP1A2GAA | |
| SCHEMBL15229339 | 0.78 | CYP1A2 (0.35) | PDE4ACYP1A2GAA | |
| SCHEMBL75745 | 0.77 | PDE4A (0.42) | PDE4AALDH1A1CYP1A2GAAPDE7A | |
| SCHEMBL10277728 | 0.74 | PDE4A (0.31) | PDE4AALDH1A1CYP1A2 | |
| SCHEMBL15229245 | 0.74 | CYP1A2 (0.37) | PDE4AALDH1A1TSHRCYP1A2GAA | |
| SCHEMBL15229581 | 0.73 | GAA (0.39) | PDE4ACYP1A2DPP4GAAPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239286-B1 | REACTING 1-AMINO-1-CYANOCYCLOPENTANE WITH AN ACYL HALIDE; THEN AN ANHYDRIDE | SANOFI-SYNTHELABO (FR) | 2001-05-29 | — | — | US | disclosed |
| US-6211382-B1 | ACYLATION OF 1-AMINO-1-CYANOCYCLOPENTANE, CYCLIZATION | SANOFI-SYNTHELABO (FR) | 2001-04-03 | — | — | US | disclosed |