SCHEMBL7745102

SCHEMBL7745102

CC(C)(C)CC(=O)CC(=O)O.CCOC(=O)CC(C)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.45
MGAM O43451 2/20 0.45
SI P14410 2/20 0.45
MGAM2 Q2M2H8 2/20 0.45
ALDH1A1 P00352 5/20 0.34
TRPA1 O75762 1/20 0.34
KDM4E B2RXH2 3/20 0.33
EGLN1 Q9GZT9 2/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
HSD11B1 P28845 1/20 0.32
PPID Q08752 1/20 0.32
MMP8 P22894 2/20 0.32
PKM P14618 1/20 0.31
CYP2D6 P10635 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21299 0.84 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
Acetoacetic Acid SCHEMBL597206 0.82 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid SCHEMBL20377480 0.82 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
Acetoacetic Acid SCHEMBL18911562 0.82 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
Acetoacetic Acid SCHEMBL18911553 0.82 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
Acetoacetic Acid SCHEMBL28635520 0.80 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
Acetoacetic Acid SCHEMBL28887750 0.80 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28876215 0.79 GAA (0.48) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL8751045 0.78 GAA (0.68) GAAMGAMSIMGAM2ALDH1A1
Acetic Acid SCHEMBL7442100 0.78 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001000684-A1 LIQUID OLIGOMERS CONTAINING UNSATURATION ASHLAND INC. (US) 2001-01-04 WO claimed