Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5922386 | 0.95 | KAT2B (0.71) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6200169 | 0.92 | KAT2B (0.81) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8654854 | 0.91 | KAT2B (0.66) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8720672 | 0.90 | KAT2B (0.78) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6198359 | 0.90 | KAT2B (0.78) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| Diethanolamine SCHEMBL198603 | 0.89 | KAT2B (0.64) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8645147 | 0.89 | KAT2B (0.67) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL110446 | 0.88 | KAT2B (0.66) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29390623 | 0.88 | KAT2B (0.66) | KAT2BALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7170020 | 0.88 | KAT2B (0.81) | KAT2BALDH1A1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-4904671-A | ANTIARTHRITIC AGENTS; PLATELET ACTIVATING FACTOR | PFIZER INC. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0330327-A2 | Dihydropyridines, their preparation and their use as PAF-antagonists | Pfizer Limited (GB) | 1989-08-30 | — | — | EP | disclosed |