Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | PON1 | P27169 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745128 | 0.84 | EGLN3 (0.48) | EGLN3HTTPDE10AHPGDDDAH1 | |
| SCHEMBL7746431 | 0.77 | HTT (0.55) | EGLN3HTTPDE10AHPGDDDAH1 | |
| SCHEMBL5858814 | 0.76 | EGLN3 (0.74) | EGLN3HTTHPGDDDAH1POLB | |
| SCHEMBL7745043 | 0.73 | RECQL (0.54) | EGLN3HTTHPGDDDAH1POLB | |
| SCHEMBL7745079 | 0.71 | CYP11B1 (0.55) | EGLN3HTTHPGDDDAH1POLB | |
| SCHEMBL1898956 | 0.71 | CNR1 (0.58) | HPGDPOLBNPC1RAB9AKDM4E | |
| SCHEMBL5859713 | 0.71 | HTT (0.59) | HTTHPGDDDAH1POLBDRD4 | |
| SCHEMBL8521785 | 0.70 | DRD4 (0.50) | HTTHPGDPOLBDRD4GAA | |
| SCHEMBL7745714 | 0.70 | KRAS (0.49) | EGLN3HTTPDE10AHPGDDDAH1 | |
| SCHEMBL29549275 | 0.70 | EGLN3 (0.65) | EGLN3PDE10ADDAH1POLBDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |