Benzene

Benzene

SCHEMBL7745548

CCOP(=O)(OCC)C1CCCN1.c1ccccc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
KCNH2 Q12809 1/20 0.35
SLC6A2 P23975 3/20 0.34
SLC6A3 Q01959 3/20 0.34
SLC6A4 P31645 2/20 0.34
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HCRTR2 O43614 2/20 0.32
ADRA2A P08913 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
TSHR P16473 1/20 0.31
DPP4 P27487 2/20 0.31
DPP8 Q6V1X1 1/20 0.31
HIF1A Q16665 1/20 0.31
ANPEP P15144 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5065199 0.95 TSHR (0.34) ADRA2ANISCHTSHR
SCHEMBL7161072 0.71 TSHR (0.40) GAAADRA2ANISCHTSHR
SCHEMBL7166475 0.71 TSHR (0.40) GAAADRA2ANISCHTSHR
SCHEMBL7166470 0.71 TSHR (0.40) GAAADRA2ANISCHTSHR
SCHEMBL416031 0.71 DPP4 (0.52) DPP4DPP8ANPEP
SCHEMBL6379222 0.68 GAA (0.35) GAAADRA2ANISCHTSHR
SCHEMBL7426176 0.67 DPP4 (0.48) SLC6A3DPP4DPP8ANPEP
SCHEMBL1243842 0.67 TSHR (0.37) TSHR
Hydrochloric Acid SCHEMBL7424349 0.66 DPP4 (0.49) SLC6A2SLC6A3TSHRDPP4DPP8
SCHEMBL2210415 0.64 TSHR (0.37) GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1064287-A1 USE OF AMINOPHOSPHONATES AS 31 P-NMR PH INDICATORS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2001-01-03 EP disclosed
WO-1999047527-A1 USE OF AMINOPHOSPHONATES AS31P NMR pH INDICATORS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CN RS) (FR) 1999-09-23 WO disclosed