Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524918 | 0.96 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL21084614 | 0.88 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL28033748 | 0.88 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL8067773 | 0.85 | TSHR (0.58) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL11242606 | 0.84 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL9853352 | 0.84 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL5835513 | 0.84 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL21313305 | 0.84 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL1548515 | 0.84 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDPOLB | |
| SCHEMBL3274720 | 0.84 | TSHR (0.56) | TSHRALDH1A1CYP3A4HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068387-A2 | MODIFIED TEXTILE AND OTHER MATERIALS AND METHODS FOR THEIR PREPARATION | Avantgarb LLC (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999049124-A2 | MODIFIED TEXTILE AND OTHER MATERIALS AND METHODS FOR THEIR PREPARATION | AVANTGARB, LLC (US) | 1999-09-30 | — | — | WO | disclosed |