Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 5/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | IGF1R | P08069 | 1/20 | 0.57 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | EEF2K | O00418 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364049 | 0.84 | ERBB2 (0.59) | ERBB2EGFRIGF1RCTRCEEF2K | |
| SCHEMBL5366009 | 0.81 | ERBB2 (0.62) | ERBB2EGFRIGF1RPLK4PLK1 | |
| SCHEMBL5360968 | 0.80 | EGFR (0.54) | ERBB2EGFRIGF1RCTRCEEF2K | |
| SCHEMBL7317553 | 0.79 | ERBB2 (0.68) | ERBB2EGFRIGF1RCTRCEEF2K | |
| SCHEMBL7317561 | 0.79 | ERBB2 (0.68) | ERBB2EGFRIGF1RCTRCEEF2K | |
| SCHEMBL5367617 | 0.79 | ERBB2 (0.53) | ERBB2EGFRIGF1RCTRCEEF2K | |
| SCHEMBL5366011 | 0.78 | ERBB2 (0.61) | ERBB2EGFRIGF1RPLK4PLK1 | |
| SCHEMBL5362776 | 0.76 | ERBB2 (0.67) | ERBB2EGFRIGF1RPLK4PLK1 | |
| SCHEMBL7311443 | 0.76 | EGFR (0.67) | ERBB2EGFRIGF1RCTRCEEF2K | |
| SCHEMBL7311437 | 0.76 | EGFR (0.67) | ERBB2EGFRIGF1RCTRCEEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021166-A1 | TREATMENT AND PREVENTION OF HEPATIC DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-03-29 | — | — | WO | disclosed |