Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366713 | 0.86 | TP53 (0.41) | TP53HSD17B10CYP3A4LMNAMEN1 | |
| SCHEMBL8363951 | 0.85 | CYP3A4 (0.44) | TP53HSD17B10CYP3A4LMNAMEN1 | |
| SCHEMBL8364966 | 0.84 | SMN1; SMN2 (0.42) | TP53HSD17B10CYP3A4LMNAMEN1 | |
| SCHEMBL8365507 | 0.84 | TP53 (0.39) | TP53HSD17B10CYP3A4LMNAMEN1 | |
| SCHEMBL8364710 | 0.83 | TP53 (0.41) | TP53HSD17B10CYP3A4LMNAUSP2 | |
| SCHEMBL7747916 | 0.82 | CYP1A2 (0.46) | TP53HSD17B10CYP3A4LMNAMEN1 | |
| SCHEMBL8365753 | 0.80 | TP53 (0.42) | TP53HSD17B10CYP3A4LMNAMEN1 | |
| SCHEMBL8365513 | 0.78 | TP53 (0.45) | TP53HSD17B10LMNAMEN1KMT2A | |
| SCHEMBL6216622 | 0.75 | ALOX5AP (0.37) | TSHRMAPK1 | |
| SCHEMBL7745456 | 0.73 | TSHR (0.61) | TP53LMNAMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |