Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 9/20 | 0.45 |
| ▸ | CA2 | P00918 | 9/20 | 0.45 |
| ▸ | CA12 | O43570 | 6/20 | 0.45 |
| ▸ | CA9 | Q16790 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13146976 | 0.97 | TDP1 (0.49) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL18484173 | 0.90 | TSHR (0.53) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL1509845 | 0.89 | MEN1 (0.50) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL12341824 | 0.87 | TDP1 (0.50) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL21065333 | 0.86 | TDP1 (0.62) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL31614625 | 0.86 | TDP1 (0.49) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL1509910 | 0.86 | MEN1 (0.50) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL26040329 | 0.85 | TDP1 (0.51) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL18471596 | 0.84 | TDP1 (0.48) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL13968020 | 0.84 | MEN1 (0.49) | TDP1MEN1GAAKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179446-B2 | Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| US-6537520-B1 | Diagnosis and treatment of cancer; kit containing compound having peptide or peptidomimetic functionality that binds to a alpha v beta 3 receptor linked to a chelator | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-03-25 | — | — | US | disclosed |