Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918514 | 0.72 | SLC7A5 (0.40) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL13031142 | 0.71 | SLC7A5 (0.44) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL13031137 | 0.71 | SLC7A5 (0.44) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL7746093 | 0.70 | SLC7A5 (0.36) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL6046223 | 0.70 | SLC7A5 (0.36) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL7746085 | 0.70 | SLC7A5 (0.36) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL3142493 | 0.65 | SLC7A5 (0.48) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL29421912 | 0.63 | SLC7A5 (0.43) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL9611983 | 0.62 | SLC7A5 (0.42) | SLC7A5PKMALPIPTGS1XIAP | |
| SCHEMBL25660543 | 0.61 | GRIA1 (0.42) | SLC7A5PKMALPIPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067950-A4 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-1067950-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999052539-A1 | NEO-TRYPTOPHAN | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1999-10-21 | — | — | WO | disclosed |