Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7746643 | 1.00 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5905510 | 0.99 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL952054 | 0.99 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4507925 | 0.99 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4792208 | 0.99 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4661498 | 0.99 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5110398 | 0.99 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL7745688 | 0.97 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL7745686 | 0.97 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 | |
| Oxalic Acid SCHEMBL7741539 | 0.95 | SLC6A2 (0.74) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001029002-A1 | PROCESS FOR THE PREPARATION OF 4-(FLUOROPHENYL)PIPERIDINE ESTERS | SMITHKLINE BEECHAM PLC (GB) | 2001-04-26 | — | — | WO | claimed |