SCHEMBL7746748

SCHEMBL7746748

NC(C(F)(F)F)C(F)(F)Br

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396567 0.76 CETP (0.32) ALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL3915727 0.64
SCHEMBL12364122 0.64
SCHEMBL18305963 0.64
SCHEMBL18306044 0.64
SCHEMBL18351724 0.62
Hydrochloric Acid SCHEMBL20531826 0.62
Hydrochloric Acid SCHEMBL20531828 0.62
SCHEMBL28765168 0.62
SCHEMBL13112936 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6300378-B1 Tropodegradable bromine-containing halocarbon additives to decrease flammability of refrigerants foam blowing agents solvents aerosol propellants and sterilants UNIVERSITY OF NEW MEXICO 2001-10-09 US disclosed
US-6031011-A Tropodegradable bromine-containing halocarbons as foam blowing agents UNIVERSITY OF NEW MEXICO (US) 2000-02-29 US disclosed
EP-0960176-A4 TROPODEGRADABLE BROMINE-CONTAINING HALOCARBON ADDITIVES TO DECREASE FLAMMABILITY OF REFRIGERANTS, FOAM BLOWING AGENTS, SOLVENTS, AEROSOL PROPELLANTS, AND STERILANTS UNIV NEW MEXICO (US) 2000-02-23 EP disclosed
EP-0960176-A1 TROPODEGRADABLE BROMINE-CONTAINING HALOCARBON ADDITIVES TO DECREASE FLAMMABILITY OF REFRIGERANTS, FOAM BLOWING AGENTS, SOLVENTS, AEROSOL PROPELLANTS, AND STERILANTS UNIVERSITY OF NEW MEXICO (US) 1999-12-01 EP disclosed
US-5900185-A Tropodegradable bromine-containing halocarbon additives to decrease flammability of refrigerants, foam blowing agents, solvents, aerosol propellants, and sterilants UNIVERSITY OF NEW MEXICO (US) 1999-05-04 US disclosed
WO-1998013437-A1 TROPODEGRADABLE BROMINE-CONTAINING HALOCARBON ADDITIVES TO DECREASE FLAMMABILITY OF REFRIGERANTS, FOAM BLOWING AGENTS, SOLVENTS, AEROSOL PROPELLANTS, AND STERILANTS THE UNIVERSITY OF NEW MEXICO (US) 1998-04-02 WO disclosed