Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110592 | 0.89 | F10 (0.56) | F10MAPTTDP1PTGS2 | |
| SCHEMBL76575 | 0.86 | F10 (0.69) | F10MAPTNPC1 | |
| SCHEMBL8314192 | 0.86 | F10 (0.59) | F10MAPTTDP1NPC1 | |
| SCHEMBL77720 | 0.84 | F10 (0.60) | F10MAPTNPC1 | |
| SCHEMBL76354 | 0.81 | F10 (0.57) | F10MAPTNPC1 | |
| SCHEMBL14311444 | 0.81 | F10 (0.51) | F10MAPTNPC1 | |
| SCHEMBL75813 | 0.80 | NPC1 (0.63) | F10NPC1PTGS2 | |
| SCHEMBL8269738 | 0.80 | NPC1 (0.63) | F10NPC1PTGS2 | |
| SCHEMBL85161 | 0.80 | F10 (0.62) | F10MAPTNPC1 | |
| SCHEMBL85110 | 0.79 | F10 (0.60) | F10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129373-B2 | Carbonyl compounds | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |