SCHEMBL7747016

SCHEMBL7747016

CCCc1ccc(CC2CCC(c3ccc(N)cc3)CC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 13/20 0.49
CYP2C9 P11712 1/20 0.41
SPHK2 Q9NRA0 7/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6751857 0.96 SPHK1 (0.46) SPHK1CYP2C9SPHK2ALDH1A1LMNA
SCHEMBL7751740 0.91 SPHK1 (0.57) SPHK1CYP2C9SPHK2MAPT
SCHEMBL7751759 0.90 SPHK1 (0.63) SPHK1SPHK2
SCHEMBL7747233 0.89 SPHK1 (0.66) SPHK1SPHK2ALDH1A1LMNAMAPT
SCHEMBL7751729 0.89 SPHK1 (0.66) SPHK1SPHK2ALDH1A1LMNAMAPT
SCHEMBL7752406 0.89 SPHK1 (0.66) SPHK1SPHK2ALDH1A1LMNAMAPT
SCHEMBL7926884 0.88 SPHK1 (0.49) SPHK1CYP2C9SPHK2ALDH1A1LMNA
SCHEMBL7747132 0.88 SPHK1 (0.41) SPHK1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7751734 0.88 SPHK1 (0.53) SPHK1CYP2C9SPHK2
SCHEMBL7747160 0.88 SPHK1 (0.64) SPHK1SPHK2ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101195711-A Polyamic acid composition and alignment film prepared from same DALI POLYMER CO LTD (CN) 2008-06-11 CN disclosed
EP-1064319-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2001-01-03 EP disclosed
EP-1042701-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2000-10-11 EP disclosed
WO-1999033902-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed
WO-1999034252-A1 POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1999-07-08 WO disclosed