Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 17/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486981 | 0.92 | FASN (0.39) | FASNPRKAA2EGLN1 | |
| Hydrochloric Acid SCHEMBL7747151 | 0.92 | FASN (0.39) | FASNPRKAA2EGLN1 | |
| SCHEMBL7594805 | 0.91 | FASN (0.45) | FASNALDH1A1 | |
| SCHEMBL7543174 | 0.90 | FASN (0.38) | FASNPRKAA2EGLN1 | |
| SCHEMBL7481462 | 0.89 | PRKAA2 (0.39) | FASNPRKAA2HPGDEGLN1 | |
| SCHEMBL7482929 | 0.88 | PRKAA2 (0.37) | FASNPRKAA2EGLN1 | |
| Hydrochloric Acid SCHEMBL7490534 | 0.87 | PRKAA2 (0.37) | FASNPRKAA2EGLN1 | |
| SCHEMBL7156162 | 0.83 | CYP19A1 (0.42) | — | |
| SCHEMBL7192093 | 0.80 | FNTA (0.46) | — | |
| SCHEMBL7121496 | 0.79 | HRH3 (0.36) | PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022963-A1 | METHOD OF PREVENTING OSTEOPOROSIS | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |