Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275775 | 0.81 | KMT2A (0.67) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| Dibenzoylmethane SCHEMBL39582 | 0.79 | MEN1 (1.00) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| Dibenzoylmethane SCHEMBL10356288 | 0.79 | MEN1 (1.00) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| Dibenzoylmethane SCHEMBL1704711 | 0.79 | MEN1 (1.00) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| SCHEMBL29035576 | 0.79 | KMT2A (0.64) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| Dibenzoylmethane SCHEMBL28139772 | 0.78 | KMT2A (0.85) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| SCHEMBL11021070 | 0.78 | TSHR (0.76) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| SCHEMBL1109662 | 0.78 | ERCC5 (0.64) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| Dibenzoylmethane SCHEMBL1628627 | 0.77 | MEN1 (0.94) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| Dibenzoylmethane SCHEMBL531257 | 0.77 | MEN1 (0.94) | KMT2AMEN1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097151-A4 | IMPROVED PROCESS FOR SYNTHESIZING CARBAPENEM INTERMEDIATES | MERCK & CO INC (US) | 2001-10-24 | — | — | EP | claimed |
| EP-1097151-A1 | IMPROVED PROCESS FOR SYNTHESIZING CARBAPENEM INTERMEDIATES | Merck & Co., Inc. (US) | 2001-05-09 | — | — | EP | claimed |
| WO-2000002880-A1 | IMPROVED PROCESS FOR SYNTHESIZING CARBAPENEM INTERMEDIATES | MERCK & CO., INC. (US) | 2000-01-20 | — | — | WO | claimed |
| EP-2755722-A2 | NOVEL SGLT INHIBITORS | Panacea Biotec Ltd. (IN) | 2014-07-23 | — | — | EP | disclosed |
| EP-2717689-A2 | NOVEL SGLT INHIBITORS | Panacea Biotec Limited (IN) | 2014-04-16 | — | — | EP | disclosed |
| WO-2013038429-A2 | NOVEL SGLT INHIBITORS | PANACEA BIOTEC LTD. (IN) | 2013-03-21 | — | — | WO | disclosed |
| WO-2012172566-A2 | NOVEL SGLT INHIBITORS | PANACEA BIOTEC LTD. (IN) | 2012-12-20 | — | — | WO | disclosed |