Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | POLB | P06746 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748692 | 1.00 | KMT2A (0.69) | KMT2APOLBLMNAMAPTGAA | |
| SCHEMBL6742684 | 0.94 | KMT2A (0.62) | KMT2APOLBLMNAMAPTGAA | |
| SCHEMBL6742685 | 0.94 | KMT2A (0.62) | KMT2APOLBLMNAMAPTGAA | |
| SCHEMBL7743096 | 0.88 | HPGD (0.68) | KMT2APOLBLMNAMAPTGAA | |
| SCHEMBL7743100 | 0.88 | HPGD (0.68) | KMT2APOLBLMNAMAPTGAA | |
| SCHEMBL23996025 | 0.87 | KMT2A (0.55) | KMT2APOLBLMNAMAPTGAA | |
| Hydrochloric Acid SCHEMBL6515900 | 0.86 | HPGD (0.66) | KMT2APOLBLMNAMAPTGAA | |
| Hydrochloric Acid SCHEMBL6515894 | 0.86 | HPGD (0.66) | KMT2APOLBLMNAMAPTGAA | |
| SCHEMBL16993689 | 0.85 | POLB (0.80) | KMT2APOLBMAPTGAATDP1 | |
| SCHEMBL16993691 | 0.85 | POLB (0.80) | KMT2APOLBMAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |