Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748784 | 1.00 | HTT (0.44) | HTTRRM1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL915349 | 0.99 | HTT (0.43) | HTTRRM1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL915348 | 0.99 | HTT (0.43) | HTTRRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL7750395 | 0.91 | HTT (0.46) | HTTRRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL7750397 | 0.91 | HTT (0.46) | HTTRRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL7750386 | 0.91 | HTT (0.47) | HTTRRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL7750378 | 0.91 | HTT (0.47) | HTTRRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL10921206 | 0.90 | HTT (0.44) | HTTRRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL10921209 | 0.90 | HTT (0.44) | HTTRRM1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10917764 | 0.88 | HTT (0.43) | HTTRRM1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |