Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748800 | 1.00 | MAPT (0.46) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL13673501 | 0.88 | MAPT (0.51) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL13673502 | 0.88 | MAPT (0.51) | MAPTALDH1A1HTTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL917359 | 0.87 | MAPT (0.50) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL7748853 | 0.87 | MEN1 (0.43) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL7748850 | 0.87 | MEN1 (0.43) | MAPTALDH1A1HTTLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL917360 | 0.87 | MAPT (0.50) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL13673582 | 0.87 | MAPT (0.46) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL13673578 | 0.87 | MAPT (0.48) | MAPTALDH1A1HTTLMNAKDM4E | |
| SCHEMBL13673580 | 0.87 | MAPT (0.48) | MAPTALDH1A1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |