Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749458 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7749633 | 0.81 | CDK2 (0.48) | P2RY1CDK2CCNE1CDK1CCNB1 | |
| SCHEMBL4572438 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7750980 | 0.77 | KDM4E (0.79) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL7749536 | 0.76 | HPRT1 (0.67) | ALDH1A1HSD17B10HPRT1MAPK1 | |
| SCHEMBL7745038 | 0.76 | HPRT1 (0.52) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL22910681 | 0.75 | CDK2 (0.48) | CDK2CCNE1CDK1CCNB1PRKACA | |
| SCHEMBL5508144 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5508152 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4572432 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019404-A4 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMW SCIENT IND RES ORG (AU) | 2001-07-04 | — | — | EP | disclosed |
| EP-1019404-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999012927-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-18 | — | — | WO | disclosed |