Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.51 |
| ▸ | FNTB | P49356 | 18/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515310 | 0.75 | FNTA (0.56) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7658441 | 0.72 | FNTA (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7655477 | 0.72 | FNTA (0.56) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL9058006 | 0.72 | FNTA (0.57) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8763074 | 0.71 | FNTA (0.47) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL6978130 | 0.71 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8763874 | 0.70 | FNTA (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7515305 | 0.70 | FNTA (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7515303 | 0.70 | FNTA (0.54) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7751678 | 0.69 | FNTA (0.47) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906099-A4 | A METHOD OF TREATING CANCER | MERCK & CO INC (US) | 2001-02-07 | — | — | EP | claimed |
| EP-0906099-A1 | A METHOD OF TREATING CANCER | Merck & Co., Inc. (US) | 1999-04-07 | — | — | EP | claimed |
| WO-1997036587-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |