Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751437 | 1.00 | RARB (0.42) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL7750464 | 1.00 | RARB (0.42) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9398977 | 0.89 | TLR9 (0.41) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9398986 | 0.89 | TLR9 (0.41) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10560165 | 0.88 | RARB (0.52) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10558978 | 0.88 | RARB (0.52) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10558236 | 0.88 | RARB (0.52) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10555705 | 0.88 | RARB (0.52) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL10554428 | 0.88 | RARB (0.52) | RARBS1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL9399114 | 0.88 | RARB (0.52) | RARBS1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| US-5759443-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-02 | — | — | US | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |