SCHEMBL7750280

SCHEMBL7750280

CC(COCc1ccccc1O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A1 P18405 5/20 0.59
SRD5A2 P31213 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9546866 0.85 SRD5A1 (0.59) SRD5A1SRD5A2
SCHEMBL8726650 0.84 SRD5A1 (0.58) SRD5A1SRD5A2
SCHEMBL8076037 0.82 SRD5A1 (0.57) SRD5A1SRD5A2
SCHEMBL8076034 0.82 SRD5A1 (0.57) SRD5A1SRD5A2
SCHEMBL8075630 0.82 SRD5A1 (0.59) SRD5A1SRD5A2
SCHEMBL8075628 0.82 SRD5A1 (0.59) SRD5A1SRD5A2
SCHEMBL8074936 0.81 SRD5A1 (0.62) SRD5A1SRD5A2
SCHEMBL8080027 0.81 SRD5A1 (0.73) SRD5A1SRD5A2
SCHEMBL8080030 0.81 SRD5A1 (0.73) SRD5A1SRD5A2
SCHEMBL8078403 0.81 SRD5A1 (0.75) SRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0649306-B1 ESTER DERIVATIVES OF 4-AZA-STEROIDS MERCK & CO INC (US) 2001-01-10 EP disclosed
US-5610162-A ENZYME INHIBITORS MERCK & CO., INC. (US) 1997-03-11 US disclosed
EP-0649306-A4 ESTER DERIVATIVES OF 4-AZA-STEROIDS. MERCK & CO INC (US) 1995-08-23 EP disclosed
EP-0649306-A1 ESTER DERIVATIVES OF 4-AZA-STEROIDS MERCK & CO. INC. (US) 1995-04-26 EP disclosed
WO-1993023041-A1 ESTER DERIVATIVES OF 4-AZA-STEROIDS MERCK & CO., INC. (US) 1993-11-25 WO disclosed