Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750369 | 1.00 | KDM4E (0.58) | KDM4EGAAHTTPARP1PARP2 | |
| SCHEMBL13673568 | 0.89 | KDM4E (0.74) | KDM4EGAAHTTPARP1PARP2 | |
| SCHEMBL13673571 | 0.89 | KDM4E (0.74) | KDM4EGAAHTTPARP1PARP2 | |
| Hydrochloric Acid SCHEMBL5702980 | 0.88 | KDM4E (0.72) | KDM4EGAAHTTPARP1PARP2 | |
| Hydrochloric Acid SCHEMBL5702973 | 0.88 | KDM4E (0.72) | KDM4EGAAHTTPARP1PARP2 | |
| Acetic Acid SCHEMBL916159 | 0.83 | KDM4E (0.66) | KDM4EGAAHTTPARP1PARP2 | |
| Acetic Acid SCHEMBL916161 | 0.83 | KDM4E (0.66) | KDM4EGAAHTTPARP1PARP2 | |
| SCHEMBL7748719 | 0.83 | HTT (0.45) | KDM4EGAAHTTALDH1A1HPGD | |
| SCHEMBL7748722 | 0.83 | HTT (0.45) | KDM4EGAAHTTALDH1A1HPGD | |
| SCHEMBL13673599 | 0.83 | KDM4E (0.54) | KDM4EGAAHTTPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |