Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750438 | 1.00 | MAPT (0.60) | MAPTKMT2ANPC1RAB9ALMNA | |
| Acetic Acid SCHEMBL915945 | 0.94 | MAPT (0.61) | MAPTKMT2ANPC1RAB9ALMNA | |
| Acetic Acid SCHEMBL915943 | 0.94 | MAPT (0.61) | MAPTKMT2ANPC1RAB9ALMNA | |
| SCHEMBL19449726 | 0.89 | MAPT (0.63) | MAPTKMT2ANPC1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL17560997 | 0.87 | MAPT (0.62) | MAPTKMT2ANPC1RAB9ALMNA | |
| SCHEMBL13611411 | 0.86 | MAPT (0.70) | MAPTKMT2ANPC1RAB9ALMNA | |
| SCHEMBL1520681 | 0.85 | MAPT (0.59) | MAPTKMT2ANPC1RAB9ALMNA | |
| SCHEMBL1520678 | 0.85 | MAPT (0.62) | MAPTKMT2ANPC1RAB9ALMNA | |
| SCHEMBL1520677 | 0.85 | MAPT (0.59) | MAPTKMT2ANPC1RAB9ALMNA | |
| Water SCHEMBL6576232 | 0.84 | MAPT (0.58) | MAPTKMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |
| US-4457859-A | LIQUID CRYSTALS, ELECTROOPTICS | IVASCHENKO ALEXANDR V (SU) | 1984-07-03 | — | — | US | disclosed |