Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750523 | 1.00 | ADORA1 (0.34) | ADORA1CXCR4PRMT5CARM1PRMT1 | |
| SCHEMBL7750517 | 1.00 | ADORA1 (0.34) | ADORA1CXCR4PRMT5CARM1PRMT1 | |
| SCHEMBL8009972 | 0.98 | ADORA1 (0.33) | ADORA1CXCR4OPRM1OPRK1CHRM1 | |
| SCHEMBL8009961 | 0.98 | ADORA1 (0.33) | ADORA1CXCR4OPRM1OPRK1CHRM1 | |
| SCHEMBL5003030 | 0.98 | ADORA1 (0.33) | ADORA1CXCR4OPRM1OPRK1CHRM1 | |
| SCHEMBL7745631 | 0.96 | CHRM1 (0.34) | ADORA1CXCR4OPRM1OPRK1CHRM1 | |
| SCHEMBL7745633 | 0.96 | CHRM1 (0.34) | ADORA1CXCR4OPRM1OPRK1CHRM1 | |
| SCHEMBL7745635 | 0.96 | CHRM1 (0.34) | ADORA1CXCR4OPRM1OPRK1CHRM1 | |
| SCHEMBL7745660 | 0.94 | PTPN1 (0.37) | ADORA1CXCR4OPRM1OPRK1CHRM1 | |
| SCHEMBL7745671 | 0.94 | PTPN1 (0.37) | ADORA1CXCR4OPRM1OPRK1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |