Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 17/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.50 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.50 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.50 |
| ▸ | NPY4R | P50391 | 6/20 | 0.45 |
| ▸ | NPY2R | P49146 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388701 | 1.00 | NPY1R (0.51) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8118603 | 0.91 | NPY1R (0.52) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL1388704 | 0.85 | TLR2 (0.42) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8126146 | 0.85 | NPY1R (0.53) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL4650743 | 0.83 | NPY1R (0.61) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL650331 | 0.83 | NPY1R (0.72) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8112493 | 0.80 | TRPV1 (0.57) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL7753042 | 0.80 | NPY1R (0.70) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8113561 | 0.80 | NPY1R (0.56) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8119423 | 0.79 | NPY1R (0.58) | NPY1RNPY5RNPFFR1NPFFR2NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | claimed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | claimed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |