Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744051 | 0.66 | CYSLTR1 (0.40) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL4078571 | 0.64 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| Acetic Acid SCHEMBL3951221 | 0.62 | GPBAR1 (0.58) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL8500737 | 0.62 | FFAR1 (0.35) | FFAR1 | |
| SCHEMBL9124616 | 0.61 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL140815 | 0.61 | CYP1A2 (0.65) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL8586332 | 0.61 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL9123403 | 0.60 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL9122067 | 0.60 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 | |
| SCHEMBL9123140 | 0.60 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2GPBAR1FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034133-A2 | ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER | ELI LILLY AND COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034134-A2 | ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER | ELI LILLY AND COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034199-A2 | ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER | ELI LILLY AND COMPANY (US) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034133-A2 | ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER | ELI LILLY AND COMPANY (US) | 2001-05-17 | — | — | WO | disclosed |