Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694058 | 0.87 | GLA (0.65) | GLAL3MBTL1RAB9ALMNAPOLB | |
| SCHEMBL9415751 | 0.85 | GLA (0.67) | GLAL3MBTL1RAB9ALMNAPOLB | |
| SCHEMBL12395359 | 0.84 | ATM (0.63) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3997411 | 0.84 | HDAC1 (0.43) | GLAHDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL15480397 | 0.82 | ATM (0.61) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL9113643 | 0.80 | GLA (0.57) | GLAL3MBTL1RAB9ALMNAPOLB | |
| SCHEMBL27415961 | 0.80 | GLA (0.57) | GLAL3MBTL1RAB9ALMNAPOLB | |
| SCHEMBL9160397 | 0.80 | GLA (0.57) | GLAL3MBTL1RAB9ALMNAPOLB | |
| SCHEMBL9113633 | 0.80 | GLA (0.57) | GLAL3MBTL1RAB9ALMNAPOLB | |
| SCHEMBL29426399 | 0.79 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066273-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048881-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-09-30 | — | — | WO | disclosed |