SCHEMBL7752132

SCHEMBL7752132

[CH2]COc1ccc(N)cc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 3/20 0.42
TSHR P16473 2/20 0.42
GAA P10253 6/20 0.38
MAPT P10636 6/20 0.38
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 4/20 0.38
CYP3A4 P08684 4/20 0.38
ESR2 Q92731 1/20 0.38
PTPN1 P18031 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
POLB P06746 2/20 0.38
CASP7 P55210 2/20 0.38
TP53 P04637 2/20 0.38
USP2 O75604 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
PDE10A Q9Y233 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550867 0.80 KDM4E (0.59) CASP1TSHRGAAMAPTKDM4E
SCHEMBL14674914 0.79 GAA (0.58) CASP1TSHRGAAMAPTKDM4E
Hydrochloric Acid SCHEMBL15486548 0.78 GAA (0.62) CASP1TSHRGAAMAPTKDM4E
SCHEMBL9794595 0.78 KDM4E (0.45) CASP1TSHRGAAMAPTKDM4E
SCHEMBL30086965 0.78 IDO1 (0.49) CASP1TSHRGAAMAPTKDM4E
SCHEMBL109612 0.78 IDO1 (0.49) CASP1TSHRGAAMAPTKDM4E
Hydrochloric Acid SCHEMBL9794533 0.77 KDM4E (0.48) CASP1TSHRGAAMAPTKDM4E
Hydrochloric Acid SCHEMBL9794562 0.77 GAA (0.47) CASP1TSHRGAAMAPTKDM4E
Water SCHEMBL9794540 0.77 IDO1 (0.47) CASP1TSHRGAAMAPTKDM4E
SCHEMBL9794555 0.77 MAPT (0.66) CASP1TSHRGAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1073407-A1 HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE ORQUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES L'OREAL (FR) 2001-02-07 EP disclosed
WO-2000038640-A1 HAIR DYEING METHOD USING AN ALIPHATIC CATIONIC AMINE AND A ALDEHYDE OR KETONE OR QUINONE OR DI-IMINO-ISOINDOLINE OR 3-AMINO-ISO-INDOLONE DERIVATIVES L'OREAL (FR) 2000-07-06 WO disclosed