SCHEMBL7752225

SCHEMBL7752225

[SiH3]C1C(c2ccco2)=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 4/20 0.34
HPGD P15428 4/20 0.34
POLB P06746 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
HSD17B10 Q99714 3/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
PKM P14618 2/20 0.34
ALOX15 P16050 2/20 0.34
CASP1 P29466 2/20 0.34
PTPN7 P35236 2/20 0.34
RECQL P46063 2/20 0.34
BLM P54132 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27709589 0.81 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL7752497 0.78 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Bromide SCHEMBL7063716 0.78 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL3671702 0.78 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7730940 0.78 CHRM2 (0.35) CHRM2CHRM4CHRM5CHRM1CHRM3
Bromide SCHEMBL7064951 0.77 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL7061669 0.77 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL7064757 0.77 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
Bromide SCHEMBL7059572 0.77 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7178895 0.77 TDP1 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1293676-A Metallocene compounds as catalyst components for olefin polymerization CHISSO CORP (JP) 2001-05-02 CN disclosed
EP-1066300-A1 METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION Chisso Corporation (JP) 2001-01-10 EP disclosed
WO-2000043406-A1 METALLOCENE COMPOUNDS AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION CHISSO CORPORATION (JP) 2000-07-27 WO disclosed