SCHEMBL775240

SCHEMBL775240

C(=CC=C1Nc2ccccc2O1)C=Cc1nc2ccccc2o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 3/20 0.49
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
DHODH Q02127 1/20 0.38
ADAMTS5 Q9UNA0 1/20 0.37
MEN1 O00255 3/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
KMT2A Q03164 3/20 0.36
APP P05067 1/20 0.36
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200971 1.00 SNCA (0.49) SNCAHDAC3HDAC4HDAC1HDAC7
Iodide SCHEMBL10580297 0.99 SNCA (0.48) SNCAHDAC3HDAC4HDAC1HDAC7
SCHEMBL75983 0.95 SNCA (0.48) SNCAHDAC3HDAC4HDAC1HDAC7
SCHEMBL4755956 0.95 SNCA (0.48) SNCAHDAC3HDAC4HDAC1HDAC7
Water SCHEMBL9843599 0.94 SNCA (0.47) SNCAHDAC3HDAC4HDAC1HDAC7
SCHEMBL7922534 0.94 SNCA (0.47) SNCAHDAC3HDAC4HDAC1HDAC7
Naphthalene SCHEMBL9806048 0.93 SNCA (0.46) SNCAHDAC3HDAC4HDAC1HDAC7
Water SCHEMBL10771784 0.93 SNCA (0.46) SNCAHDAC3HDAC4HDAC1HDAC7
Naphthalene SCHEMBL16150068 0.92 SNCA (0.45) SNCAHDAC3HDAC4HDAC1HDAC7
Anthracene SCHEMBL3834018 0.91 SNCA (0.44) SNCAHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4155397-B1 DETECTION OF NUCLEIC ACIDS UNIV MICHIGAN REGENTS (US) 2024-06-26 EP disclosed
US-20240036035-A1 ANALYTE DETECTION USING FLUOROGENIC PROBES OR MULTIPLEX TECHNOLOGIES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-02-01 US disclosed
WO-2024015860-A2 ANALYTE DETECTION USING FLUOROGENIC PROBES OR MULTIPLEX TECHNOLOGIES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-01-18 WO disclosed
WO-2024015927-A2 ANALYTE DETECTION USING APTAMERS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-01-18 WO disclosed
US-20230159611-A1 SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN RECEPTOR BEARING T CELLS (SMART CARS) YALE UNIVERSITY 2023-05-25 US disclosed
EP-4155397-A1 DETECTION OF NUCLEIC ACIDS The Regents of The University of Michigan (US) 2023-03-29 EP disclosed
US-20230070399-A1 METHODS AND SYSTEMS FOR PROCESSING TIME-RESOLVED SIGNAL INTENSITY DATA THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2023-03-09 US disclosed
EP-4121556-A1 ANALYTE DETECTION The Regents of The University of Michigan (US) 2023-01-25 EP disclosed
CN-115516107-A Analyte detection 密歇根大学董事会 2022-12-23 CN disclosed
EP-4105338-A1 DETECTION OF NUCLEIC ACIDS The Regents of The University of Michigan (US) 2022-12-21 EP disclosed
EP-1368460-A2 REAL-TIME SEQUENCE DETERMINATION Visigen Biotechnologies, Inc. (US) 2003-12-10 EP disclosed
WO-2003048868-A1 APPARATUS AND METHOD FOR DIGITAL HOLOGRAPHIC IMAGING ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2003-06-12 WO disclosed
US-20030064366-A1 Real-time sequence determination Life Technologies Corporation 2003-04-03 US disclosed
WO-2001062952-A9 METHODS FOR DETERMINING SINGLE NUCLEOTIDE VARIATIONS DNA SCIENCES INC (US) 2003-01-09 WO disclosed
WO-2002004680-A2 REAL-TIME SEQUENCE DETERMINATION VISIGEN BIOTECHNOLOGIES, INC. (US) 2002-01-17 WO disclosed
US-20010049102-A1 Methods for determining single nucleotide variations DNA SCIENCES, INC. 2001-12-06 US disclosed
WO-2001062952-A1 METHODS FOR DETERMINING SINGLE NUCLEOTIDE VARIATIONS DNA SCIENCES, INC. (US) 2001-08-30 WO disclosed
US-5270548-A Phase-sensitive flow cytometer THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1993-12-14 US disclosed
US-5206143-A Method and reagents for performing subset analysis using quantitative differences in fluorescence intensity SMITHKLINE BEECHAM CORPORATION (US) 1993-04-27 US disclosed
EP-0219309-B1 METHODS AND REAGENTS FOR PERFORMING ANALYSES OF SUBPOPULATIONS OF PARTICLES SMITHKLINE BEECHAM CORPORATION (US) 1992-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159611-A1 SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN RECEPTOR BEARING T CELLS (SMART CARS) CD47, CD4, CD2 SNCA 4704/4885HDAC3 3764/4885HDAC4 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.