SCHEMBL7752415

SCHEMBL7752415

CCOC(=O)[C@H](CNC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.71
CTSK P43235 8/20 0.53
CTSS P25774 9/20 0.52
CTSL P07711 5/20 0.52
CTSB P07858 3/20 0.52
PPARA Q07869 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30460045 0.94 SYK (0.72) SYKCTSKCTSSCTSLCTSB
SCHEMBL3897638 0.92 SYK (0.72) SYKCTSKCTSSCTSLCTSB
SCHEMBL7752671 0.91 SYK (0.60) SYKCTSKCTSSCTSLCTSB
SCHEMBL14496968 0.91 SYK (0.71) SYKCTSKCTSSCTSLCTSB
SCHEMBL479092 0.91 SYK (0.71) SYKCTSKCTSSCTSLCTSB
SCHEMBL479093 0.91 SYK (0.71) SYKCTSKCTSSCTSLCTSB
SCHEMBL1626508 0.90 SYK (0.67) SYKCTSKCTSSCTSLCTSB
SCHEMBL615358 0.89 SYK (0.72) SYKCTSKCTSSCTSLCTSB
SCHEMBL615359 0.89 SYK (0.72) SYKCTSKCTSSCTSLCTSB
SCHEMBL1890758 0.89 SYK (0.72) SYKCTSKCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725059-B1 2,3-DIAMINOPROPIONIC ACID DERIVATIVE SUMITOMO PHARMA (JP) 2001-01-17 EP disclosed
US-6048854-A ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-04-11 US disclosed
US-5707994-A USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1998-01-13 US disclosed
EP-0725059-A1 2,3-DIAMINOPROPIONIC ACID DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1996-08-07 EP disclosed