Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | KLK7 | P49862 | 4/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753603 | 0.84 | NPY5R (0.39) | SYK | |
| SCHEMBL29521579 | 0.82 | SYK (0.63) | SYKKLK7KLK5CACNA1BCTSK | |
| SCHEMBL22975065 | 0.79 | SYK (0.60) | SYKKLK7KLK5CACNA1BCTSK | |
| SCHEMBL22975064 | 0.79 | SYK (0.60) | SYKKLK7KLK5CACNA1BCTSK | |
| SCHEMBL3897638 | 0.78 | SYK (0.72) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL30460045 | 0.78 | SYK (0.72) | SYKCTSKCTSSCTSLCTSB | |
| SCHEMBL14496968 | 0.77 | SYK (0.71) | SYKKLK5CTSKCTSSCTSL | |
| SCHEMBL479093 | 0.77 | SYK (0.71) | SYKKLK5CTSKCTSSCTSL | |
| SCHEMBL479092 | 0.77 | SYK (0.71) | SYKKLK5CTSKCTSSCTSL | |
| SCHEMBL615359 | 0.76 | SYK (0.72) | SYKCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |