Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752608 | 1.00 | SRD5A1 (0.68) | SRD5A1SRD5A2 | |
| SCHEMBL8075915 | 0.89 | SRD5A1 (0.74) | SRD5A1SRD5A2 | |
| SCHEMBL8075912 | 0.89 | SRD5A1 (0.74) | SRD5A1SRD5A2 | |
| SCHEMBL8074997 | 0.87 | SRD5A1 (0.71) | SRD5A1SRD5A2 | |
| SCHEMBL8074995 | 0.87 | SRD5A1 (0.71) | SRD5A1SRD5A2 | |
| SCHEMBL7750316 | 0.86 | SRD5A1 (0.68) | SRD5A1SRD5A2 | |
| SCHEMBL7750314 | 0.86 | SRD5A1 (0.68) | SRD5A1SRD5A2 | |
| SCHEMBL8078408 | 0.86 | SRD5A1 (0.70) | SRD5A1SRD5A2 | |
| SCHEMBL8078409 | 0.86 | SRD5A1 (0.70) | SRD5A1SRD5A2 | |
| SCHEMBL7745357 | 0.86 | SRD5A1 (0.76) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649306-B1 | ESTER DERIVATIVES OF 4-AZA-STEROIDS | MERCK & CO INC (US) | 2001-01-10 | — | — | EP | disclosed |
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |
| US-5610162-A | ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0649306-A4 | ESTER DERIVATIVES OF 4-AZA-STEROIDS. | MERCK & CO INC (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0649306-A1 | ESTER DERIVATIVES OF 4-AZA-STEROIDS | MERCK & CO. INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993023041-A1 | ESTER DERIVATIVES OF 4-AZA-STEROIDS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| WO-1993023039-A1 | SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | disclosed |