Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7750465 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7751453 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7750420 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7745526 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7745560 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7745540 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7750408 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7750340 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7750045 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7751444 | 1.00 | NPC1 (0.53) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821049-B1 | Cyclopentyl compounds | ROLIC AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| US-5759443-A | Cyclopentyl derivatives | ROLIC AG (CH) | 1998-06-02 | — | — | US | disclosed |
| EP-0821049-A1 | Cyclopentyl compounds | Rolic AG (CH) | 1998-01-28 | — | — | EP | disclosed |