SCHEMBL7752840

SCHEMBL7752840

CCc1cccc2ccc(C)cc12

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.59
CYP1A2 P05177 4/20 0.59
TDP1 Q9NUW8 1/20 0.45
NR3C1 P04150 1/20 0.43
PGR P06401 1/20 0.43
NR3C2 P08235 1/20 0.43
MAPT P10636 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
CNR2 P34972 2/20 0.41
MTNR1A P48039 4/20 0.41
MTNR1B P49286 3/20 0.41
GABRA1 P14867 2/20 0.40
GABRB2 P47870 2/20 0.40
MAOA P21397 1/20 0.40
ATM Q13315 1/20 0.39
IDH1 O75874 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27919191 0.98 CYP2A6 (0.57) CYP2A6CYP1A2TDP1NR3C1PGR
SCHEMBL7838287 0.85 CYP2A6 (0.55) CYP2A6CYP1A2TDP1CNR2MTNR1A
SCHEMBL7747919 0.84 CYP1A2 (0.59) CYP2A6CYP1A2TDP1NR3C1PGR
SCHEMBL15345396 0.82 CYP2A6 (0.57) CYP2A6CYP1A2TDP1MTNR1AMAOA
Ammonia Solution, Strong SCHEMBL27919138 0.82 CYP1A2 (0.57) CYP2A6CYP1A2TDP1NR3C1PGR
SCHEMBL11586426 0.82 CYP1A2 (0.57) CYP2A6CYP1A2TDP1MTNR1AMTNR1B
SCHEMBL3277029 0.82 CYP1A2 (0.57) CYP2A6CYP1A2TDP1MTNR1AMTNR1B
SCHEMBL8573022 0.80 TDP1 (0.64) CYP2A6CYP1A2TDP1MAPTMTNR1A
Ammonia Solution, Strong SCHEMBL27919153 0.80 CYP1A2 (0.50) CYP2A6CYP1A2MAPTCNR2MTNR1A
SCHEMBL3238625 0.80 CYP1A2 (0.55) CYP2A6CYP1A2MAPTCNR2MTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3089957-A1 PURIFICATION OF AROMATIC CARBOXYLIC ACIDS BP Corporation North America Inc. (US) 2016-11-09 EP disclosed
WO-2015102654-A1 PURIFICATION OF AROMATIC CARBOXYLIC ACIDS BP CORPORATION NORTH AMERICA INC. (US) 2015-07-09 WO disclosed
EP-0710684-B1 Preparation process of polyhydroxycarboxylic acid MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
US-5770683-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-23 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed