Methane

Methane

SCHEMBL7753045

C.C1=Cc2cccc3cccc(c23)C1.C1=Cc2cccc3cccc(c23)C1

nearest known ligand 0.41

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CYP3A4 P08684 2/20 0.41
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 4/20 0.35
HPGD P15428 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
KDM4E B2RXH2 2/20 0.34
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33
TYMS P04818 1/20 0.32
LMNA P02545 1/20 0.32
PARP1 P09874 1/20 0.32
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL16297414 1.00 TSHR (0.41) TSHRCYP3A4CA1CA2ALDH1A1
Methane SCHEMBL17330285 0.98 CYP3A4 (0.40) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL27642275 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL29376031 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL27642281 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL7712 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL7432807 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL29555130 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL17685497 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1
SCHEMBL27642594 0.98 TSHR (0.43) TSHRCYP3A4CA1CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0745100-B1 PREPARATION OF POLY(ETHER-URETHANES) FROM CYCLIC ETHERS AND ORGANIC ISOCYANATES DU PONT (US) 2001-01-31 EP claimed
US-5430122-A Preparation of poly(ether-urethanes) from cyclic ethers and organic isocyanates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-04 US claimed
CN-113493542-B Conjugated diene polymer, process for producing the same, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2023-09-22 CN disclosed
CN-112979876-B Branched conjugated diene polymer and method for producing same, method for producing rubber composition, and method for producing tire 旭化成株式会社 2023-09-08 CN disclosed
CN-113493543-B Conjugated diene polymer, process for producing the same, and rubber composition 旭化成株式会社 2023-09-05 CN disclosed
CN-115348975-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2022-11-15 CN disclosed
CN-110325556-B Modified conjugated diene polymer, polymer composition, and rubber composition 旭化成株式会社 2022-05-13 CN disclosed
CN-110857344-B Modified conjugated diene polymer composition, rubber composition, and method for producing rubber composition 旭化成株式会社 2022-04-15 CN disclosed
CN-110872405-B Modified conjugated diene polymer composition, rubber composition, method for producing rubber composition, and tire 旭化成株式会社 2022-04-12 CN disclosed
CN-110862590-B Modified conjugated diene polymer composition, rubber composition, and method for producing rubber composition 旭化成株式会社 2022-04-12 CN disclosed
CN-110878151-B Rubber composition 旭化成株式会社 2022-04-12 CN disclosed
CN-110869433-A Rubber composition for tread and pneumatic tire 住友橡胶工业株式会社 2020-03-06 CN disclosed
CN-110857344-A Modified conjugated diene polymer composition, rubber composition, and method for producing rubber composition 旭化成株式会社 2020-03-03 CN disclosed
CN-110818975-A Modified conjugated diene polymer composition, method for producing modified conjugated diene polymer composition, and tire 旭化成株式会社 2020-02-21 CN disclosed
CN-110655697-A Method for producing modified conjugated diene polymer mixture 旭化成株式会社 2020-01-07 CN disclosed
CN-110506062-A MODIFIED CONJUGATED DIENE POLYMER, POLYMER COMPOSITION, AND RUBBER COMPOSITION ASAHI CHEMICAL IND 2019-11-26 CN disclosed
CN-110325556-A Modified conjugated diene polymer, polymer composition and rubber composition 旭化成株式会社 2019-10-11 CN disclosed
CN-104487506-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2019-06-07 CN disclosed
CN-108779336-A Addition-curable silicon rubber composition and solidfied material 信越化学工业株式会社 2018-11-09 CN disclosed
CN-106083927-B Phosphino- amidine compound, metal complex, antigravity system and their oligomeric or olefin polymerization purposes 切弗朗菲利浦化学公司 2018-10-26 CN disclosed