SCHEMBL7753048

SCHEMBL7753048

O=C(c1ccccc1)c1ccc(OCC(O)CO)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.58
HPGD P15428 2/20 0.58
CYP2D6 P10635 2/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
PGR P06401 1/20 0.58
SLC6A2 P23975 1/20 0.58
PDE4A P27815 1/20 0.58
CYP2C19 P33261 1/20 0.58
HRH1 P35367 1/20 0.58
HTT P42858 1/20 0.58
SLC6A3 Q01959 1/20 0.58
PDE4D Q08499 1/20 0.58
MEN1 O00255 1/20 0.54
USP2 O75604 1/20 0.54
GAA P10253 1/20 0.54
KMT2A Q03164 1/20 0.54
KEAP1 Q14145 1/20 0.54
NFE2L2 Q16236 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30069001 0.93 HPGD (0.62) MAPK1HPGDCYP2D6ALDH1A1LMNA
SCHEMBL9208030 0.93 HPGD (0.62) MAPK1HPGDCYP2D6ALDH1A1LMNA
SCHEMBL7175178 0.90 HPGD (0.47) MAPK1HPGDCYP2D6ALDH1A1LMNA
SCHEMBL12602536 0.87 HPGD (0.63) MAPK1HPGDCYP2D6ALDH1A1LMNA
Hydrochloric Acid SCHEMBL2065176 0.86 HPGD (0.58) MAPK1HPGDCYP2D6ALDH1A1LMNA
SCHEMBL6545279 0.85 HPGD (0.63) MAPK1HPGDCYP2D6ALDH1A1LMNA
SCHEMBL3294782 0.85 TSHR (0.48) MAPK1ALDH1A1LMNAGAAMAOB
SCHEMBL28977113 0.85 HPGD (0.50) MAPK1HPGDCYP2D6ALDH1A1LMNA
Oxybenzone SCHEMBL9626888 0.84 HPGD (0.79) MAPK1HPGDCYP2D6ALDH1A1LMNA
SCHEMBL6908971 0.84 HPGD (0.52) MAPK1HPGDCYP2D6ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105199349-A Polylactic acid packing materials having ultraviolet protection function and ultraviolet irradiation degradation resistance performance UNIV SICHUAN 2015-12-30 CN claimed
CN-105199349-A Polylactic acid packing materials having ultraviolet protection function and ultraviolet irradiation degradation resistance performance UNIV SICHUAN 2015-12-30 CN disclosed
US-7863478-B2 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology MERCK PATENT GMBH (DE) 2011-01-04 US disclosed
US-7863478-B2 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology MERCK PATENT GMBH (DE) 2011-01-04 US disclosed
US-20080038213-A1 Uv Filters MERCK PATENT GMBH (DE) 2008-02-14 US disclosed
US-20080038213-A1 Uv Filters MERCK PATENT GMBH (DE) 2008-02-14 US disclosed
EP-0538839-B1 Benzophenone derivative, utraviolet absorbent and external preparation for skin SHISEIDO CO LTD (JP) 2001-01-24 EP disclosed
US-5342610-A Sunscreen agent SHISEIDO CO., LTD. (JP) 1994-08-30 US disclosed
EP-0538839-A1 Benzophenone derivative, utraviolet absorbent and external preparation for skin SHISEIDO COMPANY LIMITED (JP) 1993-04-28 EP disclosed
US-4831109-A Copolymerizable UV stabilizers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-05-16 US disclosed
US-4691059-A Copolymerizable UV stabilizers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-09-01 US disclosed
EP-0213925-A2 Copolymerizable UV stabilizers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080038213-A1 Uv Filters ERCC4, ERCC1, ERCC5 MAPK1 3250/4885HPGD 385/4885CYP2D6 499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.