Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.78 |
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.76 |
| ▸ | OSBP | P22059 | 2/20 | 0.73 |
| ▸ | RORC | P51449 | 2/20 | 0.73 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.73 |
| ▸ | CRYAB | P02511 | 1/20 | 0.73 |
| ▸ | HMGCR | P04035 | 1/20 | 0.73 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.73 |
| ▸ | ITGAV | P06756 | 1/20 | 0.73 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.67 |
| ▸ | POLA1 | P09884 | 1/20 | 0.65 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31504646 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL11868717 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL8561190 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL10784914 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL11650951 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL23312299 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL8636407 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL8561197 | 1.00 | NR1H3 (0.78) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL16140022 | 0.96 | GRIN1 (0.73) | NR1H3NPC1L1OSBPRORCOSBP2 | |
| SCHEMBL14770981 | 0.96 | GRIN1 (0.73) | NR1H3NPC1L1OSBPRORCOSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077992-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058549-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |
| EP-0084199-B1 | METHOD OF PREPARING DELTA 5,7-STEROIDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-04-29 | — | — | EP | disclosed |
| US-4464298-A | Method of preparing Δ5,7-steroids | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1984-08-07 | — | — | US | disclosed |
| EP-0084199-A1 | Method of preparing delta 5,7-steroids | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1983-07-27 | — | — | EP | disclosed |
| US-4226770-A | Synthesis of steroids | KAISER EMIL T | 1980-10-07 | — | — | US | disclosed |
| US-4163744-A | Synthesis of steroids | KAISER EMIL T | 1979-08-07 | — | — | US | disclosed |
| US-4022768-A | Process for preparation of 1α,25-dihydroxycholecalciferol | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-3936478-A | Process for the preparation of desmosterol derivatives | TEIJIN LIMITED (JA) | 1976-02-03 | — | — | US | disclosed |