Niacinamide

Niacinamide

SCHEMBL7753606

NC(=O)c1cccnc1.[N]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.96
F3 P13726 1/20 0.96
SARM1 Q6SZW1 1/20 0.96
SIRT2 Q8IXJ6 1/20 0.96
SIRT6 Q8N6T7 1/20 0.96
SIRT1 Q96EB6 1/20 0.96
SIRT3 Q9NTG7 1/20 0.96
SIRT5 Q9NXA8 1/20 0.96
SIRT4 Q9Y6E7 1/20 0.96
ALDH1A1 P00352 2/20 0.63
APP P05067 1/20 0.63
GAA P10253 1/20 0.63
HCAR3 P49019 1/20 0.63
HCAR2 Q8TDS4 1/20 0.63
MKNK1 Q9BUB5 3/20 0.61
MKNK2 Q9HBH9 3/20 0.61
HDAC1 Q13547 2/20 0.57
HDAC6 Q9UBN7 1/20 0.57
POLB P06746 2/20 0.53
PLOD2 O00469 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Niacinamide SCHEMBL19978192 0.98
Niacinamide SCHEMBL2926 0.98
Niacinamide SCHEMBL460466 0.98 F7 (1.00) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL29624874 0.98
Niacinamide SCHEMBL25366418 0.96
Niacinamide SCHEMBL1220080 0.96 F7 (0.96) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL11870926 0.96 F7 (0.96) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL6702885 0.96 F7 (0.96) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL226257 0.96 F7 (0.96) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL23576525 0.96 F7 (0.96) F7F3SARM1SIRT2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841879-A Supermolecule arbutin nicotinamide, preparation method thereof and daily chemical product 深圳杉海创新技术有限公司 2025-04-18 CN disclosed
CN-118580185-A Method for synthesizing 3-cyanopyridine oxynitride by microreactor 南京理工大学 2024-09-03 CN disclosed
CN-114010636-B Application of nicotinamide compound in preparation of medicines for treating herpes simplex encephalitis 暨南大学 2023-05-26 CN disclosed
EP-0662830-B1 (pi)-BOND AROMATIC VITAMIN CHELATES ALBION INT (US) 2001-01-24 EP disclosed
EP-0662830-A4 -G(P)-BOND AROMATIC VITAMIN CHELATES. 1995-08-16 EP disclosed
EP-0662830-A1 $g(p)-BOND AROMATIC VITAMIN CHELATES ALBION INTERNATIONAL, INC. (US) 1995-07-19 EP disclosed
US-5292729-A Pi bond vitamin-mineral chelates ALBION INTERNATIONAL, INC. (US) 1994-03-08 US disclosed
WO-1994004141-A1 π-BOND AROMATIC VITAMIN CHELATES ALBION INTERNATIONAL, INC. (US) 1994-03-03 WO disclosed