Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 20/20 | 0.71 |
| ▸ | KCNA5 | P22460 | 14/20 | 0.71 |
| ▸ | KCNA4 | P22459 | 2/20 | 0.71 |
| ▸ | KCNA1 | Q09470 | 2/20 | 0.71 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.71 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.71 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.71 |
| ▸ | KCNA7 | Q96RP8 | 1/20 | 0.71 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503682 | 1.00 | KCNA3 (0.71) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL2586445 | 0.86 | KCNA3 (0.76) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL23406793 | 0.85 | KCNA3 (0.69) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL4123742 | 0.84 | KCNA3 (0.68) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL2579695 | 0.83 | KCNA3 (0.78) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL29410610 | 0.83 | KCNA3 (1.00) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL25981033 | 0.83 | CYP2D6 (0.68) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL2583446 | 0.83 | KCNA3 (1.00) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL2579673 | 0.83 | KCNA3 (1.00) | KCNA3KCNA5KCNA4KCNA1KCNN4 | |
| SCHEMBL2585454 | 0.83 | KCNA3 (1.00) | KCNA3KCNA5KCNA4KCNA1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001053301-A1 | CHIMERIC MOLECULES CONSISTING OF PSORALEN AND RETINOID, PREPARATION METHOD, USES THEREOF FOR TREATING CELL HYPERPROLIFERATION PATHOLOGIES AND IN PARTICULAR PSORIASIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-07-26 | — | — | WO | claimed |
| CN-113214282-B | AChE/BACE1/GSK3 beta three-target inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2022-03-22 | — | — | CN | disclosed |
| CN-113214282-A | AChE/BACE1/GSK3 beta three-target inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2021-08-06 | — | — | CN | disclosed |
| WO-2001053301-A1 | CHIMERIC MOLECULES CONSISTING OF PSORALEN AND RETINOID, PREPARATION METHOD, USES THEREOF FOR TREATING CELL HYPERPROLIFERATION PATHOLOGIES AND IN PARTICULAR PSORIASIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2001-07-26 | — | — | WO | disclosed |