SCHEMBL7754262

SCHEMBL7754262

c1ccc(C2(c3ccccc3)CCCCC2C2CCCCC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.41
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28261290 0.77 ALOX5AP (0.39) SIGMAR1
SCHEMBL13379647 0.76 ESR2 (0.42) SIGMAR1
SCHEMBL9825525 0.75 AKR1C1 (0.46) SLC6A2SLC6A4
SCHEMBL9501520 0.75 SLC6A4 (0.38) SIGMAR1SLC6A2SLC6A4SLC6A3
SCHEMBL8090093 0.74 CNR2 (0.41)
SCHEMBL1955880 0.74 SLC18A3 (0.47)
SCHEMBL1954906 0.74 SLC18A3 (0.47)
SCHEMBL1958981 0.74 SLC18A3 (0.47)
SCHEMBL12276561 0.74 SLC18A3 (0.47)
SCHEMBL1958752 0.74 SLC18A3 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0037902-B1 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1986-06-18 EP claimed
JP-57049688-A None JP disclosed
JP-57119975-A None JP disclosed
JP-59159879-A None JP disclosed
EP-0708107-B1 Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition SHINETSU CHEMICAL CO (JP) 2001-02-28 EP disclosed
US-5856432-A Polyimide film from pyromellitic dianhydride and a bis (4-aminophenoxy) aromatic compound as an alignment layer for liquid crystal displays E. I. DUPONT DE NEMOURS AND COMPANY (US) 1999-01-05 US disclosed
US-5731404-A Polyimide film from pyromellitic dianhydride and a bis(4-aminophenoxy) aromatic compound as an alignment layer for liquid crystal displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-24 US disclosed
EP-0772074-A1 Polyimide film from pyromellitic dianhydride and bis(4-aminophenoxy) aromatic compound as an alignment layer for liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-05-07 EP disclosed
US-5624601-A Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-04-29 US disclosed
EP-0708107-A1 Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-04-24 EP disclosed
EP-0361255-A1 Liquid-crystal mixtures containing azulene square acid dye BASF Aktiengesellschaft (DE) 1990-04-04 EP disclosed
EP-0199111-B1 LIQUID CRYSTAL COMPOSITIONS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-09-20 EP disclosed
US-4778619-A Liquid crystal compositions MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1988-10-18 US disclosed
US-4726659-A Display device having different alignment layers RCA CORPORATION (US) 1988-02-23 US disclosed
EP-0199111-A2 Liquid crystal compositions MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1986-10-29 EP disclosed
US-4601547-A Used in a field effect negative display liquid crystal display element SEIKO EPSON CORPORATION (JP) 1986-07-22 US disclosed
EP-0187015-A2 Squarilium compound and liquid crystal composition containing the same MITSUBISHI KASEI CORPORATION (JP) 1986-07-09 EP disclosed
JP-S59159879-A LIQUID CRYSTAL COMPOSITION SEIKO EPSON CORP 1984-09-10 JP disclosed
JP-S57119975-A LIQUID CRYSTAL DISPLAY ELEMENT TOSHIBA CORP 1982-07-26 JP disclosed
JP-S5749688-A LIQUID CRYSTAL DISPLAY ELEMENT TOSHIBA CORP 1982-03-23 JP disclosed