SCHEMBL7754499

SCHEMBL7754499

C=CCC(Cl)(Cl)C(C)(C)O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064490 0.74
SCHEMBL629470 0.72 MAPT (0.36) MAPT
SCHEMBL1537973 0.71
SCHEMBL6514869 0.71
SCHEMBL5440182 0.71
SCHEMBL991394 0.71
SCHEMBL8244794 0.71
SCHEMBL125434 0.71
SCHEMBL30907077 0.70 MAPT (0.35) MAPT
SCHEMBL6262274 0.70 MAPT (0.32) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001056982-A1 VITAMIN D-DERIVATIVES AND THEIR USE IN TREATING OSTEOPOROSIS AND RELATED BONE DISORDERS LEO PHARMA A/S (DK) 2001-08-09 WO disclosed
EP-0662953-B1 NOVEL VITAMIN D ANALOGUES LEO PHARM PROD LTD (DK) 1997-06-18 EP disclosed
US-5612325-A ANTIINFLAMMATORY AND IMMUNOMODULATING EFFECTS Leo Pharmaceutical Products Ltd. A/S (L.o slashed.vens Kemiske Fabrik Produktionsaktieselskab) (DK) 1997-03-18 US disclosed
EP-0662953-A1 NOVEL VITAMIN D ANALOGUES. LEO PHARM PROD LTD (DK) 1995-07-19 EP disclosed
WO-1994007851-A1 NOVEL VITAMIN D ANALOGUES Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) 1994-04-14 WO disclosed