Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TPMT | P51580 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758456 | 0.85 | TTR (0.62) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL31395250 | 0.85 | TPMT (0.54) | TTRTSHRTPMTHCAR1DAO | |
| SCHEMBL10300670 | 0.79 | TTR (0.56) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL983707 | 0.78 | TTR (0.72) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL4507939 | 0.76 | TPMT (0.54) | TTRTSHRTPMTHCAR1DAO | |
| SCHEMBL1573147 | 0.76 | TTR (0.62) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL31701026 | 0.76 | TTR (0.52) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL867170 | 0.76 | TTR (0.52) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL16994423 | 0.76 | TTR (0.52) | TTRTSHRTPMTSRD5A2PLAU | |
| SCHEMBL23699484 | 0.76 | TPMT (0.45) | TTRTSHRTPMTHCAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056982-A1 | VITAMIN D-DERIVATIVES AND THEIR USE IN TREATING OSTEOPOROSIS AND RELATED BONE DISORDERS | LEO PHARMA A/S (DK) | 2001-08-09 | — | — | WO | disclosed |